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Sleep, often the cornerstone of good health, is deeply influenced by a complex interplay of hormones and biological rhythms. Among these, cortisol, often called the stress hormone, plays a significant yet underappreciated role.
Secreted by the adrenal glands, cortisol follows a precise 24-hour cycle, aligning with our circadian rhythms to regulate wakefulness, alertness, and the transition to rest. However, when this rhythm is disrupted—whether due to lifestyle factors, stress, or sleep disorders—the consequences ripple through every aspect of our physical and mental well-being.
Dr Yatin Sagvekar, Consultant Neurology at Kokilaben Dhirubhai Ambani Hospital, Navi Mumbai, explained the intricate relationship between cortisol, the stress hormone, and sleep. With its pivotal role in maintaining our circadian rhythms and overall health, cortisol is a hormone of significant influence in sleep-wake cycles.
Cortisol follows a daily rhythm, peaking in the morning around 8 am. It begins to rise during the latter half of sleep, helping to stimulate wakefulness as you transition out of sleep. Throughout the day, cortisol levels gradually decline, reaching their lowest point near midnight, coinciding with your body’s natural sleep drive, said Dr Sagvekar.
This rhythm is a cornerstone of sleep health, ensuring you remain alert during the day and relaxed enough for restorative sleep at night. Disruption to this rhythm, such as through stress or lifestyle factors, can significantly impact your sleep quality.
Cortisol production is regulated by the hypothalamic-pituitary-adrenal (HPA) axis, which operates at low levels during the evening to prepare the body for sleep. However, disturbances to the HPA axis—whether due to stress, clinical sleep disorders like obstructive sleep apnea (OSA), or poor sleep habits—can alter this balance.
According to Dr Sagvekar, chronic sleep loss and HPA axis hyperactivation have been linked to obesity and type II diabetes. Elevated cortisol levels can interfere with glucose metabolism and insulin sensitivity, contributing to these conditions. Cortisol’s immunosuppressive effects can lead to increased susceptibility to infections.
To optimise cortisol rhythms and promote restful sleep:
DISCLAIMER: This article is based on information from the public domain and/or the experts we spoke to. Always consult your health practitioner before starting any routine.