Some headway, but more needs to be done, say docs

This is the first time a large number of genes has been located which may effect pathogenesis of diabetes. But experts here agree that it is too early to promise any relief to patients.

8220;This study is a large study, and points to a large number of genes. However, we need to look at these studies critically and in overall perspective,8221; says said Dr Anoop Misra, Director and Head, Department of Diabetes and Metabolism, Fortis Hospitals. 8220;We already know that diabetes is a polygenic disease with gene-lifestyle interactions, and several genes contribute to it and this new discovery only adds to a long list of predisposing genes and genetic polymorphisms,8221; he adds. What is critical is whether this and similar discoveries will lead to any immediate relief for patients, whether they will lead to new diagnostic tests to say which person is going to develop diabetes and new treatments. 8220;The answer is 8220;no8221;. These process, and better understanding of causes of diabetes based on this new discovery will take a long time,8221; Misra said.

Another expert points to the need of further such studies to identify all the genes involved. 8220;We have identified certain genes which are predisposing factors for the disease. The day we will be able to identify the genes responsible for diabetes we will be able to find out the treatment. There is more that needs to be done in the same direction,8221; said Dr AK Jhingan, director, Delhi Diabetes Research Centre.