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This is an archive article published on April 30, 2012

Breastfeeding protects babies against cancer: study

Breastfeeding prevents certain childhood cancers,such as lymphoblastic leukemia,Hodgkin's disease.

Breastfeeding has many health benefits. Mothers,now,add one more to the list — it protects babies against various forms of cancer,say researchers.

A new study found high levels of cancer-fighting TNF-related apoptosis inducing ligand (TRAIL) in human milk,which the researchers say may be one of the sources of breast milk’s anti-cancer activity.

For the study in the ‘Journal of Human Lactation’,published by SAGE,the researchers took samples of colostrum,the first milk available to newborns,and of mature breast milk from new mothers.

They then obtained samples of blood from healthy women,and various ready-to-feed infant formulas. The colostrum,mature breast milk,blood and formula were then all tested to measure their level of TRAIL.

The researchers found that colostrum and breast milk contained 400 and 100-fold,respectively,higher levels of TRAIL than blood. No TRAIL was detected in the formula.

“The important role of breastfeeding in the prevention of certain childhood cancers,such as lymphoblastic leukemia,Hodgkin’s disease,and neuroblastoma,has been previously demonstrated,” the researchers say.

“However,endogenous soluble TRAIL represents a strong candidate to explain the overall biological effect of breastfeeding against cancer,” they added.

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Mothers chosen to participate in the study were eligible because they exhibited no signs of eclampsia,infection,or fever,and delivered healthy newborns at term.

The researchers said: “To our knowledge,this is the first time that TRAIL has been measured in colostrum and human breast milk. This study has revealed much higher TRAIL concentrations in colostrum and breast milk compared to the levels of circulating serum TRAIL.”


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