Many newly diagnosed type 2 diabetes patients look for alternative ways to manage the chronic health issue, much like a Quora user who asked, 'Is raw onion better than metformin for type-2 diabetics?' So, we decided to verify with experts. Endocrinologist Dr Sanjay Kalra concurred and admitted that many of his patients "ask me if raw onions can replace metformin in type 2 diabetes." The answer, however, "is no—it cannot replace it, but it may complement it. Metformin remains the gold standard first-line therapy for type 2 diabetes. It has been proven in large clinical trials to consistently reduce HbA1c, improve fasting and postprandial glucose levels, and lower long-term cardiovascular risk. Its mechanisms, reducing liver glucose output, improving insulin sensitivity, and decreasing intestinal glucose absorption, are well established and supported by decades of evidence," said Dr Kalra. Interestingly, onions (Allium cepa), especially when consumed raw, show promising hypoglycemic properties. "For instance, a clinical study demonstrated that consuming 100 g of raw red onion significantly reduced fasting blood glucose levels in type-2 diabetic patients within a few hours. Laboratory studies also suggest that onion compounds can inhibit enzymes like a-amylase and a-glucosidase, slowing carbohydrate digestion and reducing post-meal glucose spikes," said Dr Kalra. However, the difference lies in strength, consistency, and evidence base. Dr Kalra asserted that metformin’s effects are predictable and scalable, and it has been studied for years in thousands of patients worldwide. "Onion’s effects, while interesting, are variable, short-term, and mainly studied in small groups or animal models. To see the benefits, one might need to consume large amounts daily, which can cause gastrointestinal discomfort and is not practical for many," said Dr Kalra. Dr Vijay Negalur, HoD, Diabetology, KIMS Hospitals, Thane, affirmed that raw onion is generally safe, fibre-rich, antioxidant, and vitamin-rich; it can help normalise the proportion of sugar spikes in blood and lower the risk of heart disease. However, overuse can cause stomach trouble or acidity in some individuals. "Nature has its benefits, but relying only on food and not taking prescribed medication is risky. The answer lies in balance, where food is utilised to supplement, not replace medication," said Dr Negalur. So, while Dr Kalra encourages patients to include onions and other vegetables in their diet for overall metabolic health, "they are best used as an adjunct, not a replacement for prescribed medications like metformin". "The safest approach is to view onions as part of a supportive diet, alongside proven therapy, rather than a standalone cure," said Dr Kalra. DISCLAIMER: This article is based on information from the public domain and/or the experts we spoke to. Always consult your health practitioner before starting any routine.
