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This is an archive article published on December 20, 2007

145;Virgin146; birth stem cells may offer tissue bank

Human egg cells can be tweaked to give rise to valued stem cells that match the tissue types of many different groups of people...

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Human egg cells can be tweaked to give rise to valued stem cells that match the tissue types of many different groups of people, US and Russian researchers reported on Wednesday. They said the stem cells they have created from unfertilised human eggs look and act like embryonic stem cells.

And they have been carefully tissue-matched in the same way as bone marrow donations to prevent the risk of rejection if they are transplanted into people.

The team at California-based International Stem Cell Corp hopes to create a bank of tissue-matched stem cells that could be used as transplants that a patient8217;s immune system would accept.

8220;The process is efficient, it is relatively safe and it is ethically sound,8221; Jeffrey Janus, president and director of research at the company, said in a telephone interview. The cells are created by a process known as parthenogenesis, a word that comes from Latin and Greek roots meaning virgin beginning.

It involves chemically tricking an egg into developing without being fertilised by sperm.

Writing in the journal Cloning 038; Stem Cells, Janus and colleagues say they have created four lines, or batches, of stem cells that have specific immune properties. The closer the match, the less likely a transplant will be rejected.

 

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