As you all know now, Vitamin D is an essential micronutrient that plays a vital role in maintaining our overall health, strengthening our immunity, bones and reducing inflammation, which, if unchecked, could be a precursor to heart disease. However, understanding the differences between various forms of vitamin D can be confusing, especially with the availability of separate supplements for vitamin D2 and vitamin D3.
Vitamin D is a fat-soluble vitamin that helps the body absorb calcium, which is crucial for building and maintaining healthy bones. It also supports muscle function, nerve function and the immune system. Unlike most vitamins, our bodies can produce vitamin D when our skin is exposed to sunlight. However, due to various factors like limited sun exposure, skin colour, age and geographic location, many people do not get enough vitamin D from sunlight alone and need to obtain it from their diet or supplements.
Vitamin D comes in two primary forms: vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol).
Vitamin D2 (Ergocalciferol): This is primarily found in plant sources and fortified foods. Mushrooms, which contain ergosterol (a compound found in fungi and plants), exposed to sunlight or UV light are a good natural source. Many fortified foods, such as milk, orange juice and cereals also contain vitamin D2. This is less effective than vitamin D3 in raising vitamin D levels in your blood. It has a short-term function.
Vitamin D3 (Cholecalciferol): This is found in animal sources, such as fatty fish (like salmon and mackerel), fish liver oil, egg yolk and beef liver. It is also synthesised in the skin when exposed to sunlight. Vitamin D3 is produced in the skin from 7-dehydrocholesterol, a compound present in the skin, when exposed to UVB rays from the sun. Vitamin D3 is more effective than vitamin D2 in raising and maintaining vitamin D levels in your blood. It has a longer duration of action.
Since vitamin D3 is more effective at raising and maintaining vitamin D levels in the blood, it is generally the preferred choice for supplementation. Studies have shown that vitamin D3 is about twice as effective as vitamin D2 in increasing blood levels of vitamin D.
If you prefer a plant-based supplement, vitamin D2 is the way to go, suitable for vegans and vegetarians. However, many people prefer vitamin D3 because it is more potent and provides longer-lasting effects. But if you have chronic kidney disease, then doctors prefer to give you D2.
Consult a healthcare provider to determine which form and dosage are appropriate for your specific needs.