Seedorf will be going head to head with a man he knows well from his playing days.
Arsenal look to break first knockout-round jinx when they play holders Bayern Munich.
Both Manchester City and Barcelona were boosted by the return of important players after injury.
Six stadiums to be finalised after eight stadiums being shortlisted for the World Cup.
City, with 117 goals in 40 games, hosts a Barcelona side that has netted just six fewer this season.
The other last-eight clash is between Sunderland, who ousted Southampton 1-0 on Saturday, and Brighton and Hove Albion on Monday.
The result against Manchester City completed a difficult week for Chelsea manager Jose Mourinho.
Lionel Messi struck twice at Nou Camp to take his total in Spain's top flight to 228 goals from 263 matches.
Mourinho has been in a war of words with Pellegrini over their respective title chances, Financial Fair Play.
The most open Premier League championship race for years continued on a wild and windy night across Britain.
Struck by missile from crowd, Ronaldo still takes Real to Cup final.
Real, who have not conceded a goal in this season's competition, are likely to meet Barcelona in April's showpiece.
Chelsea now have 57 points from 26 matches, two ahead of Arsenal, who host Manchester United on Wednesday.
Arsenal lost top spot in the league after a 5-1 humiliation by a rampant Liverpool at Anfield.
Fulham first stunned Old Trafford in the 19th minute when Steve Sidwell scored to leave seventh-place United facing a ninth loss of its title defense.
Real lost Marcelo to injury before Mario fired Villarreal back into the contest as the home team sat back.
Chelsea are top with 56 points, followed by Arsenal on 55, City with 54 and Liverpool on 50.
The chances of Arsene Wenger’s side ending their nine-year wait for a trophy will be clearer by the end of a gruelling month.
Atletico had beaten Real at the Santiago Bernabeu in last year’s final.
IOC President Thomas Bach has launched a wide review of the organisation as a way to revamp it.
Swansea’s 2-0 defeat at West Ham United on Saturday was their sixth in eight league games.
Chelsea end City’s home run to go level with hosts and just two behind Arsenal.
Simeone’s side go top for the first time in 17 years; Madrid held at Bilbao.
Bayern stretched its record league unbeaten run to 44 games and the win was its 17th from 19 games this season.
The win sets up Arsenal for a challenging period, with Liverpool, United and Bayern coming up in next 4 fixtures.






