What is Cushing’s Syndrome, which actor Amy Schumer has been diagnosed with?

What’s the syndrome all about?

Dr Puneet Bhuwania, consultant nephrologist and transplant physician at Wockhardt Hospitals, Mira Road described Cushing’s syndrome as a complex and rare condition caused by prolonged exposure to high levels of cortisol in the body. “This hormone, produced by the adrenal glands, plays a key role in regulating metabolism and immune function. However, excessive cortisol can lead to a range of symptoms such as weight gain, muscle weakness, and mood swings.”

One pertinent aspect of Cushing’s syndrome is its diverse range of causes from tumours in the pituitary or adrenal glands to external factors like certain medications. “While the physical symptoms of Cushing’s syndrome are often noticeable, its psychological impact is equally significant. Patients may experience cognitive impairments, memory problems, and even depression or anxiety. The challenges faced by individuals with this condition extend beyond the physical realm, highlighting the importance of holistic care and support systems,” said Bhuwania.

Apart from weight gain, muscle weakness, and mood swings, patients may sometimes experience uncontrolled blood pressure (representative) (Source: Getty Images/Thinkstock)

Apart from weight gain, muscle weakness, and mood swings, patients may sometimes experience uncontrolled blood pressure. “It is crucial for individuals experiencing these symptoms to seek medical attention promptly as untreated Cushing’s syndrome can lead to serious health complications,” noted Dr Bhuwania.

Treatment options for Cushing’s syndrome vary depending on the underlying cause. According to Dr Bhuwania, in some cases, surgery may be required to remove tumours causing excessive cortisol production. “Other treatment approaches include medication to suppress cortisol production or radiation therapy for certain types of tumours. Patients with Cushing’s syndrome need to work closely with their healthcare providers to develop a personalised treatment plan that addresses their specific needs and concerns,” he said.