NEW DELHI, MAR 1: The government has decided to de-license the manufacture of five bulk drugs - Vitamin B1, Vitamin B2, Tetracycline, Oxytetracycline and Folic Acid. The entrepreneurs who wished to avail the de-licensing facility would be required to file an Industrial Entrepreneurs' Memorandum (IEM) in the industry ministry, an official release said here today. Those who have been issued letters of intent (LoI) for manufacture of any or all of the five bulk drugs need not file an initial IEM, the release said. The government has recently decided to exempt the five bulk drugs from reservation.