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This is an archive article published on December 15, 2006

Circumcision halves HIV risk, says new US study after Africa trials

Circumcision appears to reduce a man’s risk of contracting AIDS from heterosexual sex by half, United States government health officials have said

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Circumcision appears to reduce a man’s risk of contracting AIDS from heterosexual sex by half, United States government health officials have said, and the directors of the two largest funds for fighting the disease said they would consider paying for circumcisions in high-risk countries.

The announcement was made by officials of the National Institutes of Health as they halted two clinical trials, in Kenya and Uganda, on the ground that not offering circumcision to all the men taking part would be unethical. The success of the trials confirmed a study done last year in South Africa.

AIDS experts immediately hailed the finding. “This is very exciting news,” said Daniel Halperin, an HIV specialist at the Harvard Center for Population and Development, who has argued that circumcision slows the spread of AIDS in the parts of Africa where it is common.

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Uncircumcised men are thought to be more susceptible because the underside of the foreskin is rich in Langerhans cells, sentinel cells of the immune system, which attach easily to the human immunodeficiency virus, which causes AIDS. The foreskin also often suffers small tears during intercourse.

But experts also cautioned that circumcision is no cure-all. It only lessens the chances that a man will catch the virus; it is expensive compared to condoms, abstinence or other methods; and the surgery has serious risks if performed by folk healers using dirty blades, as often happens in rural Africa. Circumcision is “not a magic bullet, but a potentially important intervention,” said Kevin M De Cock, director of HIV/AIDS for WHO.

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