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Discover why South Asia’s elderly face high mortality from diarrhoeal diseases despite global progress. Learn about the risks, causes, and preventive measures. (Source: Freepik)A recent study published in The Lancet Infectious Diseases revealed a stark reality: despite significant progress in reducing global deaths from diarrhoeal diseases, older adults remain highly vulnerable, particularly in South Asia.
This demographic, coupled with children under five, continues to account for the highest mortality rates worldwide.
The study, based on the comprehensive Global Burden of Disease (GBD) analysis conducted by the Institute for Health Metrics and Evaluation (IHME), highlighted that in 2021, diarrhoeal diseases caused 1.2 million deaths globally—a remarkable decrease from 2.9 million in 1990. However, the decline wasn’t evenly distributed across all demographics or regions.
In South Asia, factors like limited access to clean water, poor sanitation, and inadequate healthcare infrastructure exacerbate these risks. (Representational)
Dr. Manisha Arora, Director of Internal Medicine at CK Birla Hospital, Delhi, explains that older adults are particularly susceptible to immunosenescence, or the natural decline in immune function. This issue is further compounded by pre-existing conditions such as kidney disease or heart disease, which complicate hydration management during diarrhoeal episodes.
“Older adults often face a dilemma during diarrhoea,” says Dr Arora. “Conditions like heart failure may require limited fluid intake, yet hydration is critical during diarrhoeal episodes. This contradiction, combined with a reduced thirst mechanism and limited mobility, increases the risk of dehydration and its complications, including kidney failure and multi-organ failure.”
In South Asia, factors like limited access to clean water, poor sanitation, and inadequate healthcare infrastructure exacerbate these risks. Older adults often suffer from malnutrition, underlying health conditions, and social isolation, further elevating their vulnerability.
To reduce mortality rates among the elderly, especially in vulnerable regions like South Asia, a multifaceted approach is essential, Dr Arora said:
While global deaths from diarrhoeal diseases have seen a dramatic decline, the challenges faced by older adults, especially in South Asia, highlight the need for focused interventions. As Dr Arora points out, “Addressing dehydration, improving healthcare access, and promoting preventive measures are key to reducing mortality rates among the elderly.”


