Antibiotic resistance has been responsible for over seven lakh deaths worldwide in the past years. (File)
For the first time, global health experts are calling on world leaders to set specific country-level targets limiting antibiotic consumption in order to combat a looming crisis of drug-resistant “superbugs”.
The proposal, which appears in Thursday’s issue of Science, is aimed at heads of state set to convene September 21 for the United Nations High-Level Meeting on Antimicrobial Resistance, where they will map out a plan for preserving global access to effective infection-fighting drugs.
Specifically, the Science analysis recommends that all countries exceeding current median global consumption of antibiotics—22 standard units per capita per year—reduce their antibiotic use to that level. Doing so would lower overall use by an estimated 21 per cent globally without negatively affecting countries that have limited access to antibiotics.
The cost of antibiotic treatment and mortality due to resistance are increasing worldwide The greatest burden occurs in low- and middle-income countries (LMICs), especially among the young: An estimated 214,000 neonatal sepsis deaths are attributable to resistant pathogens each year. But high-income countries are not immune: An estimated 23,000 people in the United States and 25,000 in Europe die each year from resistant pathogens.
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In the past year, antibiotic resistance has been responsible for over seven lakh deaths worldwide including 2,14,000 sepsis related deaths of infants four weeks or younger. In addition, more than one million children die annually from untreated pneumonia and sepsis because they cannot gain access to effective antibiotics, according to experts calling for action.
Achieving global targets for antibiotic resistance should be a key element of the UN plan, according to the proposal authors, who include Ramanan Laxminarayan, director for the Center for Disease Dynamics, Economics & Policy, and Martin Blaser, director of New York University’s Human Microbiome Program and chair of the President’s Advisory Council on Combating Antibiotic-Resistant Bacteria. The September 21 marks only the third time in history that the UN has used its convening power to bring heads of state together on a health issue, Laxminaryan said.





