This is a weight loss story of a patient that caught me by surprise. A 35-year-old young man, weighing over 100 kg and with grade III fatty liver, dropped 20 kg in three months and went down to grade I. He showed that with consistent effort in maintaining diet, exercise and sleep discipline, it’s possible to reverse fatty liver.
Remember there is no treatment for fatty liver as such and lifestyle correction continues to be the most effective pill. When the young man came to my clinic, he had high cholesterol, triglycerides, obesity, prediabetes, sleep apnea and elevated liver enzymes, which indicate that the liver is working under duress. Yet he said he did not drink at all. He had classic signs of Non-Alcoholic Fatty Liver Disease (NAFLD), a condition where too much fat is stored in liver cells even when you do not drink a drop. This is becoming common among Indians who battle conditions like genetics, insulin resistance, cholesterol and obesity, all of which stress out the liver. That’s why non-alcoholic fatty liver disease (NAFLD) is now called the metabolic dysfunction-associated steatotic liver disease (MASLD).
My young patient had a sedentary job with a work-from-home routine. Compounding his couch woes were a family history of obesity and a very poor diet. He would have no less than three colas a day along with chocolate and ice cream. He couldn’t sleep at nights, binge-watching shows on OTT, saying that was his only leisure time.
Though his liver enzymes like SGOT, SGPT and GGT were elevated, he said his levels had never been this high. That’s because in NAFLD, the fat buildup doesn’t translate to significant liver cell damage in the earlier stages. That’s why we quantify fat through an ultrasound called the FibroScan.
My patient began by changing his food, consulting a nutritionist and shifting to a Mediterranean-style diet. He mostly had steamed and grilled food, stopped ordering food or dining outside and gave up sugary beverages, even pre-mixes of tea and coffee. He gave up all forms of processed and packaged foods though ready-to-eat pouches were his favourite once. He drastically cut down the carbohydrate content in his meals, increased lean protein, fibre-rich fruits, vegetables, included whole grains and healthy fats. Snacking was only about having fibre. He made sure to have his last meal by 6 pm, come what may. He disconnected himself from his phone by 10 pm and slept by 10.30 pm.
Losing 10 per cent of your current body weight can dramatically decrease the amount of fat in the liver. My patient began slow and steady, attempting 30-minute walks, then going up to an hour. Then he took up weight training and cardio alternating them over six days.
He took up HIIT (High-Intensity Interval Training), like push-ups, squats and burpees, which are very effective in burning fat, including liver fat. He added stress management techniques like meditation, deep breathing and took up pottery as a hobby.
Most important, he kept his changes gradual to prevent negative side effects from rapid changes.
We gave him saroglitazar, which is not a cure but can reduce liver stiffness, improve liver enzymes and decrease liver fat content. We supported that with Vitamin E and Omega 3 fatty acid supplements. But in the end, he amended the basic tenets of his life and felt restored and confident.
(Dr Tickoo is Director, Internal Medicine, Max Healthcare)