Novak Djokovic had his 30 match winning streak in Grand Slams interrupted by American Sam Querrey to lose in the third round of Wimbledon. The reigning champion and number 1 seed lost 6-7, 1-6, 6-3, 6-7 to the big serving Querrey in a little under three hours. Querrey next faces Frenchman Nicolas Mahut - the man known for playing the longest match in Open Era. Here's how Twitter reacted to the Serbian's surprising loss. Novak Djokovic's Grand Slam record since 7th June 2015: WWWWWWWWWWWWWWWWWWWWWWWWWWWWWWL#Wimbledon — Wimbledon (@Wimbledon) July 2, 2016 Andy Murray's chances of winning Wimbledon again just massively improved. #djokovic — Piers Morgan (@piersmorgan) July 2, 2016 What a match by Sam Querrey to break the many Djokovic streaks…congrats Sam! Too bad for Novak…28 grand slam quarterfinals in a row… Wow — Martina Navratilova (@Martina) July 2, 2016 Querrey accidentally got Lendl's coffee this morning at breakfast. No need to say more. #thelendleffect — Bruno Soares (@BrunoSoares82) July 2, 2016 HOLY QUERREY!!!! So happy for this guy 😍. pic.twitter.com/4z9d7nAtPC — Nicole Gibbs (@Gibbsyyyy) July 2, 2016 Sam the MAN pic.twitter.com/JJVx177FvD — John Isner (@JohnIsner) July 2, 2016 Big Sam isn't enough now. That was massive Sam — James Blake (@JRBlake) July 2, 2016 Holy Upset Batman!!! Wow #Querrey #Wimbledon well earned go #🇺🇸 — Jan-Michael Gambill (@JanmikeGambill) July 2, 2016