The gene that could grow new teeth ‘discovered’

In fact,according to lead scientist Chrissa Kioussi of the Oregon State University,“It’s not unusual for a gene to have multiple functions,but before this we did not know what regulated the production of tooth enamel. “This is the first transcription factor ever found to control the formation and maturation of ameloblasts,which are the cells that secrete enamel.” The team made the link by studying mice genetically engineered to lack the gene. The animals were born with rudimentary teeth which were ready to erupt but lacked a proper covering of enamel.

The findings,published in the Proceedings of the National Academy of Sciences journal,can be applied to human health and,if used in conjunction with fledgling stem cell technology,could one day allow people to grow replacement teeth when needed.

Alternatively,the knowledge could be used to strengthen and repair existing enamel,cutting decay and the need for fillings.

“Enamel is one of the hardest coatings found in nature. A lot of work would still be needed to bring this to human applications,but it should work. It could be really cool,a whole new approach to dental health,” Dr Kioussi said.