Scientists in Germany have developed a microchip sensor that can be implanted close to a tumour to monitor its growth,a feat they say could lead to less aggressive and more targeted cancer treatments.
Developed by researchers at the Technical University in Munich,the tiny sensor tracks oxygen levels in nearby tissue to detect if a tumour is expanding.
Results are then transmitted wirelessly to a patients doctor,which the researchers said,would reduce the need for frequent hospital scans,the BBC reported.
Future designs will include a medication pump that can deliver drugs directly to the affected area,the researchers said.
Dr Sven Becker,who led the team that developed the sensor,said: There are some tumours which are hard to remove,for example,close to the spine. You run the risk of cutting the nerve if you remove them surgically. Or the problem may be that the tumour is growing slowly,but the patient is elderly.
In these cases its better to monitor the tumour,and only treat it if theres a strong growth phase. According to the scientists,the sensor is implanted next to a tumour,and it measures the concentration of dissolved oxygen in nearby tissue fluid. If this drops it can indicate aggressive growth,and doctors can be alerted.
The microelectronic chip has a set of electrodes that detect oxygen saturation. It transmits this sensor data to an external receiving unit thats like a small box you carry around in your pocket, explained Dr Becker.
From there it goes into the doctors PC — and they can look at the data and decide whether the tumour activity is getting worse. The researchers believe this will reduce the need for frequent hospital check-ups and prove more effective and less toxic for future cancer patients,Normally you would have to go to the hospital to be monitored — using machines like MRI to detect the oxygen saturation. With our system you can do it on the go, said Dr Becker.
The team now plans to add a medication pump to the chip that can release chemotherapeutic drugs close to a tumour if treatment is needed.
Dr Becker hopes this will prove more effective and less toxic for future cancer patients In traditional chemotherapy you put drugs into the whole body — which can have awful side effects. We want to add a pump to our chip,so if the sensor detects growth,you can apply microscopic amounts directly to the tumour, he said.
Patients can be treated more quickly and with less side effects,because its local. Development is still in its early stages,but researchers hope to have a device ready for medical use within ten years.