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This is an archive article published on July 12, 2005

China tests new HIV medication

A Chinese company has started clinical trials of a new HIV/AIDS medication which it claims can prevent the deadly HIV virus from entering im...

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A Chinese company has started clinical trials of a new HIV/AIDS medication which it claims can prevent the deadly HIV virus from entering immune cells.

After four-years of research, Dr. Zhou Genfa, chairman of the Tianjin-based Fusogen Pharmaceuticals, says they have developed a vaccine which functions as an HIV fusion inhibitor.

‘‘Normally, the HIV virus invades the human body by fusing with the cell’s membrane,’’ said Gao Fu, Microbiology Research Institute chief of the Chinese Academy of Sciences, speaking yesterday at a meeting on new HIV/AIDS medication in Beijing.

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‘‘So the key is to safeguard the ‘gate’ and prevent the occurrence of membrane fusion,’’ he was quoted as saying by China Daily.

The medication can target the HIV membrane fusion protein and prevent the virus from attacking cells. AIDS patients and those who are HIV positive will need to be injected everyday, Zhou said.

Zhou said he had been inspired by T20, the first drug in a new class of fusion inhibitors developed by an American company which was granted marketing approval by the US Food and Drug Administration in March 2003.

But, the Chinese medication, which has been registered as a new medicine with the state food and drug administration, employs a totally different molecular modelling.

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And its price will be ‘‘significantly’’ lower than T20 which can cost $20,000 per patient per year, he said. The new medication is likely to hit the market at the end of next year, the report said.

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