Fulham vs Blackburn Rovers
Bottom-placed Blackburn Rovers have won only once in 10 games since Mark Hughes became manager six weeks. Fulham have lost to Chelsea and Everton since their 4-1 win at Newcastle three weeks ago.
Bolton Wanderers vs Portsmouth
Portsmouth are reeling following the sudden resignation of manager Harry Redknapp on Wednesday. Director of football Velimir Zajec will take charge of the team and his immediate task will be to a halt a run of three successive league defeats.
Charlton Athletic vs Chelsea
Charlton won the corresponding fixture 4-2 last season but will do well to gain a point against the league leaders whose eight-match winning streak in all competitions ended with a 2-2 draw against Bolton last week.
West Brom Albion vs Manchester United
WBA stunned Arsenal at Highbury last week with a late goal from to force a 1-1 draw and ex-Manchester United legend Bryan Robson — their manager — will be desperate to beat his old club, which qualified for the knockout phase of the Champions League on Tuesday.
Southampton vs Crystal Palace
Becoming the first team to lose to Norwich this season only increased the pressure on Saints coach Steve Wigley. He badly needs his side to beat Palace, who have lost their last three cup and league matches and are scrambling to get clear of the relegation zone.
Birmingham City vs Norwich City
Norwich won their first league game of the season last week and might fancy their chances at St Andrews where Birmingham have only won once in the league this season.
Manchester City vs Aston Villa
Aston Villa moved up to fifth after a third successive league win against Spurs on Monday and will need to show similar form to get past their former goalkeeper David James and his in-form Manchester City colleagues.