Planning a wedding involves a whirlwind of emotions, logistics, and details, but one crucial element often neglected is a thorough evaluation of liver function. Dr Adithya V. Naragund, Senior Consultant in GI & HPB Surgery at Cytecare Hospitals, Bengaluru, highlights the significance of the SGPT test as part of premarital health screenings. What is the SGPT Test? Dr Naragund explains, "The SGPT test, also known as the ALT test, measures the level of Alanine Aminotransferase (ALT), an enzyme primarily found in the liver that plays a vital role in converting proteins into energy. When liver cells are damaged or inflamed, ALT leaks into the bloodstream, serving as a critical marker for liver health." He adds that healthcare providers utilize the SGPT test to diagnose and monitor liver diseases such as hepatitis, cirrhosis, and fatty liver disease. Elevated ALT levels may indicate liver damage or dysfunction, but can also be linked to other conditions like muscle injury or heart disease. The test involves a simple blood draw, with results typically available within a day. It is often included in a routine liver function panel, which offers valuable insights into overall liver health and guides further diagnostic or treatment decisions. Why is the SGPT test important before marriage? Dr Naragund emphasizes the necessity of the SGPT test prior to marriage, stating, "This test helps assess liver health, allowing both partners to be aware of any potential liver issues that could impact their future well-being. Liver diseases can be asymptomatic in the early stages, and undiagnosed conditions can lead to serious health complications later on. By undergoing this test, couples can identify any liver dysfunctions, facilitating timely medical intervention." He further points out that understanding one’s liver health can prevent the transmission of infectious diseases such as hepatitis B and C - critical factors for marital planning and future family health. Proactively addressing liver health fosters transparency and trust between partners, ensuring a healthier start to married life. Normal range and interpreting results Dr Naragund clarifies that the normal range for SGPT (ALT) levels typically falls between 7 to 56 units per liter of blood, although this can vary slightly based on the laboratory and specific testing methods. He contextualises the results for premarital screening: "Normal SGPT levels indicate healthy liver function, providing reassurance to both partners. Conversely, abnormal results, especially elevated levels, may suggest liver inflammation or damage due to conditions like hepatitis, fatty liver disease, or alcohol-related liver damage." Dr Naragund stresses the need for further investigation in cases of elevated SGPT levels, saying, "In the context of premarital screening, abnormal results necessitate additional testing to identify the underlying cause. Addressing liver health issues before marriage is essential for preventing potential health complications and ensuring the well-being of both partners. Prompt medical attention and lifestyle adjustments can often manage or treat the underlying condition, paving the way for a healthier married life." By incorporating the SGPT test into premarital health screenings, couples can make informed decisions about their future and prioritize their health, setting the stage for a happy and healthy marriage. DISCLAIMER: This article is based on information from the public domain and/or the experts we spoke to. Always consult your health practitioner before starting any routine.