This is what happens to the body if you mix and drink different types of alcohol

How does mixing alcohol impact the body?

“The idea that mixing alcohols is inherently harmful is a myth. What truly matters is the total volume consumed and the pace of drinking,” says Kanikka Malhotra, consultant dietician & diabetes educator.

The body processes alcohol using enzymes such as alcohol dehydrogenase and aldehyde dehydrogenase, which convert ethanol into acetaldehyde, a toxic byproduct. The effects of mixing alcohol are less about the combination itself and more about the total quantity consumed. Switching between types of alcohol can often mask the sense of overconsumption, leading to higher blood alcohol concentration (BAC). Here’s how that affects our bodies.

Short-term consequences of mixing alcohol

1. Increased Risk of Intoxication

Mixing beverages like beer and spirits may encourage excessive consumption, overwhelming the liver’s ability to metabolise alcohol. This leads to elevated BAC, impairing judgement, coordination, and reaction time, says Fiona Sampat, Clinical Dietitian at Kokilaben Dhirubhai Ambani Hospital.

2. Dehydration

Alcohol acts as a diuretic, increasing urine output. Combined with inadequate hydration, this can cause severe dehydration, leading to headaches, dizziness, and fatigue, Malhotra said.

3. Stomach Irritation

According to Sampat, alcohol irritates the stomach lining, and mixing drinks may exacerbate gastric discomfort, causing nausea, acidity, and gastritis.

4. Cognitive and Motor Impairment

As BAC rises, brain function slows, impacting mood, behaviour, and motor coordination. Malhotra says this raises the risk of accidents and poor decision-making.

5. Alcohol Poisoning

Overconsumption from mixed drinks increases the risk of alcohol poisoning, Sampat said, which is a life-threatening condition characterised by confusion, vomiting, and slowed breathing.

While abstinence is the safest route, moderation and mindful drinking are crucial. (Source: Freepik)

Long-term consequences of mixing alcohol

1. Liver Damage

Prolonged heavy drinking—whether mixing or not—stresses the liver. Chronic alcohol use can lead to conditions such as cirrhosis, fatty liver, and alcoholic hepatitis, according to Malhotra.

2. Gastrointestinal Issues

Frequent alcohol use damages the stomach lining, hindering nutrient absorption and leading to chronic gastric discomfort and ulcers.

3. Cognitive Decline

Alcohol impairs brain function over time, causing memory loss, cognitive decline, and conditions like Wernicke-Korsakoff syndrome, linked to Vitamin B1 deficiency, says Sampat.

4. Cardiovascular Risks

Excessive alcohol consumption increases the likelihood of high blood pressure, stroke, and heart disease, whether mixed or consumed in large quantities of a single type.

Certain individuals should completely abstain from mixing or even consuming alcohol. Other than pregnant women and individuals with chronic conditions like liver disease, heart problems, etc, those on medications should completely stay away from it. “Alcohol can intensify the effects of some medications, leading to severe side effects or toxicity,” warns Sampat.

Guidelines for responsible alcohol consumption

While abstinence is the safest route, moderation and mindful drinking are crucial. Here are some tips:

• Monitor Intake: Be aware of the total alcohol consumed, regardless of the type.
• Stay Hydrated: Drink water alongside alcohol to minimise dehydration.
• Eat Before Drinking: Food slows alcohol absorption, reducing intoxication risks.
• Avoid Mixing: Stick to one type of alcohol to maintain a better sense of consumption.
• Know Your Limits: Recognise your body’s tolerance and avoid overindulgence.

DISCLAIMER: This article is based on information from the public domain and/or the experts we spoke to. Always consult your health practitioner before starting any routine.