Is there a link between antidepressants and weight gain?

A major review of 151 clinical studies involving over 58,000 participants has revealed significant variations in the side effects of different antidepressants. While some medications may lead to weight gain, others could result in weight loss. Understanding these differences is crucial for patients and healthcare providers when considering treatment options. (Source: Photo by Unsplash, reference from US news and world report )

Weight Gain Variations Among Antidepressants: The study found that patients taking certain antidepressants experienced up to 2 kg (4.5 lbs) of weight gain within the first two months of treatment, while others lost a similar amount. For instance, agomelatine was associated with weight loss, whereas maprotiline led to weight gain in nearly half of the users. (Source: Photo by Unsplash, reference from US news and world report )

Physical Side effects Observed: Heart rate becomes a 21 beat per minute difference between fluvoxamine and nortriptyline. Blood pressure becomes an 11 mmHg difference between nortriptyline and doxepin. (Source: Photo by Unsplash, reference from US news and world report )

Implications for Long Term Use: Long term use of antidepressants can lead to cumulative side effects. Regular monitoring and open communication with healthcare providers are essential to manage and mitigate these effects over time. (Source: Photo by Unsplash, reference from US news and world report )

Importance of Personalised Treatment: The findings emphasize the need for personalized antidepressant prescriptions. Patients should be informed about potential side effects, including weight changes, to make collaborative decisions with their healthcare providers. (Source: Photo by Unsplash, reference from US news and world report )

Recommendations for Patients: Patients experiencing significant side effects should consult their healthcare providers. Adjusting the medication type or dosage may help balance therapeutic benefits with manageable side effects. (Source: Photo by Unsplash, reference from US news and world report )

Weight Gain among Antidepressants: The study found that patients taking certain antidepressants experienced up to 2 kg (4.5 lbs) of weight gain within the first two months of treatment, while others lost a similar amount. For instance, agomelatine was associated with weight loss, whereas maprotiline led to weight gain in nearly half of the users. (Source: Photo by Unsplash, reference from US news and world report )