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Muscle loss is a natural part of ageing, beginning subtly in our 30s with a condition known as sarcopenia. Dr Manisha Arora, director of internal medicine at CK Birla Hospital, Delhi, explains that several factors contribute to this decline. The decreasing levels of growth hormones and testosterone, essential for muscle maintenance and repair, lead to a reduction in muscle-building efficiency. Coupled with a general decrease in physical activity, these hormonal changes make it increasingly difficult for the body to maintain muscle mass.
On average, individuals in their 30s and 40s lose about 1–2% of their muscle mass per year. As they progress into their 50s, this rate accelerates to 3–4%, and by their 60s, muscle mass may decrease by as much as 4–5% annually. These rates vary, but without intervention, age-related muscle loss can lead to significant health impacts, Dr Arora said.
However a lesser-known consequence of losing muscle mass is an increased risk of type 2 diabetes. Muscle tissue is vital in glucose metabolism, as it absorbs glucose from the bloodstream. With less muscle, there is reduced tissue available for glucose uptake, resulting in higher blood sugar levels, Dr Arora explained. This can lead to insulin resistance, a condition where cells respond inadequately to insulin, making it harder for glucose to enter the cells, thus increasing the risk of diabetes.
Muscle loss also reduces glycogen synthesis—the process by which glucose is stored in muscles. With impaired glycogen storage, the body struggles to regulate blood sugar levels efficiently. Chronic inflammation, often associated with sarcopenia, further worsens insulin resistance, accelerating the path toward type 2 diabetes. A 2018 meta-analysis published in the Journal of Clinical Endocrinology and Metabolism even found that sarcopenia increases diabetes risk by 24%, especially in older adults.
While muscle loss is a natural part of aging, proactive lifestyle choices can significantly slow this process and help mitigate related health risks. Dr Arora recommends effective strategies to maintain muscle mass and support metabolic health:
By implementing these lifestyle adjustments, it’s possible to maintain muscle mass, support metabolic health, and reduce the risk of conditions like type 2 diabetes.
DISCLAIMER: This article is based on information from the public domain and/or the experts we spoke to. Always consult your health practitioner before starting any routine.