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A limited study conducted by the Indian Council of Medical Research (ICMR) among 18 participants has found that a combination of Covishield and Covaxin shots is safe and, in fact, offers better immunogenicity than two doses of the same vaccine.
The researchers, however, have made it clear that the evidence is very limited and called for multi-centre randomised clinical trials to conclusively prove the findings.
This study comes months after several people in Uttar Pradesh received Covishield as the first dose followed by inadvertent administration of Covaxin as the second dose.
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Dr Rajni Kant, director of ICMR’s Regional Medical Research Centre, Gorakhpur, and lead author, told The Indian Express that this was a small study involving 18 participants.
They received a vaccination regimen of Covishield followed by Covaxin. The participants did not report any adverse event following immunization and demonstrated high antibody response.