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New Lancet study: How banning sale of tobacco products can prevent 40% of lung cancer deaths

Preventing 1.2 million lung cancer deaths: New Lancet study highlights impact of a smoke-free generation

Lung cancerIndia could further strengthen its efforts by enhancing measures like more rigorous monitoring of smoking prevalence, increasing taxes on tobacco products, and expanding the number of smoke-free spaces. (File photo)

When 40-year-old Nilesh (name changed) from Delhi started hacking up thick, phlegmy coughs, he knew it was time to see a doctor. The fear of lung cancer loomed, but tests cleared him of that—though the warning was clear: his ten-a-day cigarette habit was a ticking time bomb. Urged to quit, Nilesh joined a three-month counselling program.

“Nilesh was committed to our sessions, and I had his wife and mother by his side to help prevent any relapses. Social events, like parties, can be tempting, but with his family as his anchor, he managed to quit,” says Dr Arvind Kumar, Chairman of the Institute of Chest Surgery and Lung Transplantation at Medanta Hospital.

Nilesh’s case underscores the urgency of tackling smoking-related health issues, a concern echoed in a recent study published in The Lancet Public Health. The new modelling study, led by researchers from the University of Santiago de Compostela, the International Agency for Research on Cancer, and global collaborators, shows that creating a generation of non-smokers could prevent 1.2 million lung cancer deaths worldwide.

Lung cancer prevalence

Lung cancer is the second most diagnosed cancer and the leading cause of cancer deaths globally, claiming around 1.8 million lives annually. Tobacco smoking is the primary culprit, responsible for over 67% of lung cancer deaths in 2019.

In India, a report from the Indian Journal of Medical Research (2022) reveals that one in nine people are likely to face a cancer diagnosis in their lifetime, with lung cancer ranking highest among men, according to the National Cancer Registry Programme.

A Lancet report cited lung cancer as the second most diagnosed cancer worldwide in 2020. In Southeast Asia, though it ranked third in new cases (185,636), it led in cancer deaths, causing 166,260 fatalities. In India, lung cancer accounts for 72,510 new cases and 66,279 deaths annually. Beyond tobacco, long-term exposure to air pollution, particularly particulate matter, is an increasingly recognised risk factor.

The study findings

The study raises a red flag, suggesting that banning the sale of cigarettes and other tobacco products to people born between 2006 and 2010 could prevent 40% of all lung cancer deaths in 185 countries by 2095.

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This birth cohort includes 650 million people, and estimates indicate that 1.2 million lung cancer deaths—40% of those expected among this generation—could be avoided if smoking were eliminated. “Lung cancer is a major killer worldwide, with a staggering two-thirds of deaths linked to one preventable risk factor: tobacco smoking,” said Dr Julia Rey Brandariz, lead author from the University of Santiago de Compostela, Spain.

Dr Isabelle Soerjomataram, Deputy Head of the Cancer Surveillance Branch at IARC and senior author of the study said: “While high-income countries had a higher proportion of potentially avoidable lung cancer deaths (61.1%), the largest number of avoidable deaths occurred in low- and middle-income countries, accounting for 65% of all preventable lung cancer deaths globally.”

Why are the findings significant for India?

“We estimate that in India, 235,100 lung cancer deaths (5.1 per 100,000 population) will occur in the study birth cohort (born between 2006 and 2010). Of these, 153,600 deaths (6.5 per 100,000 population) will occur in males, and 81,500 deaths (3.6 per 100,000 population) in females. According to the study’s findings, approximately 4,200 deaths (1.8%) could be averted in India. Among men, 3,100 deaths (2.0%) would be prevented, while among women, 1,100 deaths (1.3%) could be avoided,” Dr Julia said in an email response to The Indian Express.

Dr Julia noted that India is one of the countries where the percentage of lung cancer deaths that could be averted by implementing a tobacco-free generation is lower than in neighbouring countries like Iran or Kazakhstan.

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“This can be explained by the fact that India has a comparatively lower lung cancer mortality rate than other countries (according to GLOBOCAN 2022 data, the rate is 5.3 deaths per 100,000 population), and these are the figures we use in our estimates, which may affect our results,” Dr Julia explained. She also referenced the latest WHO report on the tobacco epidemic, published in 2023, which states that tobacco use prevalence in India is 6%.

Dr Julia also highlighted that the WHO report on the tobacco epidemic shows India has achieved a high level of compliance with measures such as tobacco dependence treatment and health warning labels. “However, India could further strengthen its efforts by enhancing measures like more rigorous monitoring of smoking prevalence, increasing taxes on tobacco products, and expanding the number of smoke-free spaces. These actions have proven effective in reducing tobacco use,” she said.

Anuradha Mascarenhas is a journalist with The Indian Express and is based in Pune. A senior editor, Anuradha writes on health, research developments in the field of science and environment and takes keen interest in covering women's issues. With a career spanning over 25 years, Anuradha has also led teams and often coordinated the edition.    ... Read More

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