Follow Us:
Monday, August 02, 2021

Environmental,genetic factors behind ‘Syndrome X’

The early stages of metabolic syndrome include increase in weight and waist size and hypertension.

Written by Ishi Khosla |
November 16, 2013 3:06:51 am

Ishi khosla is a former senior nutritionist at Escorts. She heads the Centre of Dietary Counselling and also runs a health food store. She feels that for complete well-being,one should integrate physical,mental and spiritual health. According to her: “To be healthy should be the ultimate goal for all.”

In the recent past,I have come across several individuals who suffer from abdominal obesity combined with one or few of the following disorders — elevated blood pressure,low HDL (good cholesterol),high LDL (bad cholesterol),high triglycerides,impaired fasting or elevated blood sugar and a family history of diabetes. The constellation of these clinical and biochemical abnormalities is referred to as metabolic syndrome or ‘Syndrome X’.

The early stages of metabolic syndrome include increase in weight and waist size and hypertension. Most of the susceptible people have at least 2-3 components of the metabolic syndrome,and with age,they develop into the full blown disease,if not addressed.

Simply put,metabolic syndrome is not a disease,rather a combination of risk factors leading to obesity,diabetes and cardiovascular disease. Over the last three decades,substantial research has been done to explain the root causes and inter-relationships of obesity,diabetes and cardiovascular disease. Dr Gerald Reaven in 1988 provided the basis for the concept of metabolic syndrome and labelled insulin resistance as its underlying cause.

Being insulin resistant means,the body does not respond to the affects of the given quantity of insulin (the blood glucose regulating hormone). This means that your pancreas (insulin secreting glands) need to produce more insulin than normal to control your blood sugars when you consume carbohydrates or excessive calories.

A combination of environment and genetic factors act together to cause metabolic syndrome. However,over the past half century,increased sedentary lifestyle and unlimited access to calories have blossomed the genes of insulin resistance into an epidemic of metabolic syndrome.

Screening for metabolic syndrome is important because of its relationship with cardiovascular disease,hypertension and diabetes as it increases the risk to suffer a heart attack.

On the more positive side,there is evidence that it can be completely reversed with healthy eating,physical activity and stress management.

📣 The Indian Express is now on Telegram. Click here to join our channel (@indianexpress) and stay updated with the latest headlines

For all the latest News Archive News, download Indian Express App.

  • The Indian Express website has been rated GREEN for its credibility and trustworthiness by Newsguard, a global service that rates news sources for their journalistic standards.