Endocrinologist explains why people regain weight after dieting

Expert explains why restrictive diets may deliver short-term results but rarely lead to lasting weight loss.

DietWhy does going on a diet doesn't work in the long run? (Photo: Freepik)
3 min readDelhiDec 31, 2025 06:30 PM IST First published on: Dec 26, 2025 at 11:30 PM IST

People start diets hoping to lose weight for good, but most end up regaining what they lost within a few days. Restrictive eating plans might work quickly at first, but their long-term failure is not about willpower. Instead, it happens because these diets contradict how our bodies naturally function.

According to Dr Monika Sharma, Senior Consultant – Endocrinology at Aakash Healthcare, the problem lies in how most diets are designed. “The human body is not meant to tolerate prolonged restriction,” she explains. “When it perceives calorie deprivation, it activates survival mechanisms that actively resist weight loss.”

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Why restrictive diets trigger weight regain

Dr Sharma explains, “From a physiological standpoint, extreme calorie restriction signals to the body that it is in a state of starvation. In response, metabolism slows down to conserve energy. Hunger-regulating hormones are disrupted—ghrelin, which stimulates appetite, rises, while leptin, which signals fullness, drops. This hormonal imbalance makes persistent hunger almost inevitable. At the same time, rapid weight loss often includes loss of muscle mass, which further reduces metabolic rate.”

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