The Menin breakthrough: How a newly identified brain protein could reverse aging

Scientists have recently become interested in Menin because research suggests that it may influence brain function, memory, learning, and healthy ageing. 

Menin protein can reverse brain agingMenin protein can reverse brain aging. (Magnific)
3 min readNew DelhiJun 6, 2026 09:28 AM IST First published on: Jun 6, 2026 at 09:26 AM IST

A newly identified brain protein may play a major role in how the body ages. According to the latest research published in PLOS Biology, a study led by Lige Leng and colleagues at Xiamen University in China focused on Menin, a protein that helps suppress brain inflammation. The results of the study, conducted primarily on mice, suggest that Menin may act as a protective “anti-ageing” factor inside the brain.

The researchers also found that declining levels of Menin in the hypothalamus triggered inflammation, memory problems, bone loss, and other ageing-related changes in mice. This represents a breakthrough in fighting age-related health decline.

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