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This is an archive article published on August 9, 2023

Study on MIND diet for cognitive improvement in older persons gives mixed results

According to clinical psychologist Aishwarya Raj, more research is needed to fully understand long-term effects and mechanisms

MIND DIETLet's take a look at what comprises MIND diet (Source: Getty Images/Thinkstock)

Up until now, findings from observational studies have suggested that dietary patterns may offer protective benefits against cognitive decline, even as data from clinical trials are limited. However, a new study that offers an insight into the Mediterranean–DASH Intervention for Neurodegenerative Delay, known as the MIND diet, (which is a hybrid of the Mediterranean diet and the DASH (Dietary Approaches to Stop Hypertension diet, as a way to reduce the risk of dementia) suggests the results are less stellar than expected.

The study published in The New England Journal of Medicine mentioned that while the MIND diet did improve the brains of those in the controlled group who followed it for three years, it had a similar effect on those who did not — indicating that the results were mixed.

“We really expected that the MIND diet would show an effect above the control group, so we were quite surprised by the outcome,” said lead study author Lisa Barnes, associate director of the Alzheimer’s Disease Research Centre at Rush University Medical Center in Chicago in the study statement.

For the analysis, the study had a two-site, randomised, controlled trial involving older adults without cognitive impairment but with a family history of dementia along with a body-mass index greater than 25, and a suboptimal diet.

The results indicated that magnetic resonance imaging (MRI) scans showed fewer white matter hyperintensities (tiny lesions) and a larger volume of both grey matter (the brain’s cognitive center) and white matter (the brain’s communication highway).

diet Can diet improve cognitive health? (Source: Pixabay)

Perhaps, there is more to know as the authors advised discretion while analysing the results.

Noting that past studies have shown that both the MIND diet and the Mediterranean diet significantly reduced the risk of cognitive decline and Alzheimer’s disease, the authors emphasised that the previous ones had a much longer duration of assessment that lasted for 10-15 years.

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The paper was presented at the 2023 Alzheimer’s International Conference in Amsterdam in July.

The authors pointed out that people in the new study’s control group may have improved their own diet instead of sticking to instructions to eat as they always had.

What is MIND diet and what do we need to know?

The MIND diet emphasises consuming leafy greens and other vegetables which are rich in antioxidants and nutrients that support brain health, said Aishwarya Raj, clinical psychologist as she listed some of the sources.

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–  Berries: Rich in compounds that may help protect the brain from oxidative stress and inflammation.

– Whole grains: Provide a steady source of energy and nutrients for brain cells.

– Nuts: Contain healthy fats, antioxidants, and vitamins that support cognitive function.

– Fish: Rich in omega-3 fatty acids, which are beneficial for brain health.

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– Poultry: Lean sources of protein are recommended over red meat.

– Olive oil: A source of healthy fats and antioxidants.

– Wine (in moderation): Some studies suggest moderate wine consumption may have neuroprotective effects.

Aishwarya said that the MIND diet recommends avoiding red meat, butter and margarine, cheese, pastries and sweets, and fried or fast food.

“While there is no guaranteed way to prevent cognitive decline, the MIND diet’s focus on nutrient-rich foods may contribute to overall brain health. Studies suggest that following the MIND diet closely is associated with a reduced risk of cognitive decline and a slower rate of cognitive impairment in older adults. However, more research is needed to fully understand its long-term effects and mechanisms. Always consult a healthcare professional before making significant dietary changes,” said Aishwarya.

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