People with psoriasis often have elevated levels of cytokines and immune system proteins that promote inflammation in the city (Source: Pixabay)
Psoriasis, a skin disease that causes a rash with itchy and dry patches, may increase the risk of heart disease, if severe. In the largest investigation to date on the association between severe psoriasis and coronary microvascular dysfunction, researchers have established the link between the condition with cardiovascular risk.
Published in Elsevier’s Journal of Investigative Dermatology, the study included 503 psoriasis patients with no clinical cardiovascular illness who received transthoracic Doppler echocardiography to assess coronary microcirculation. As per the researchers, more than 30 per cent of asymptomatic patients had coronary microvascular dysfunction.
The research findings indicated that the Psoriasis Area Severity Index (PASI) score, as well as the duration of the disease, were both independently linked to reduced coronary flow reserve (CFR). Additionally, the presence of psoriatic arthritis was also associated with lower CFR.
According to experts, the link between psoriasis and heart disease lies in chronic inflammation. “Psoriasis is an autoimmune skin condition characterised by inflammation, and this chronic inflammation can affect the entire body, including blood vessels,” Dr Vikas Chopra, senior consultant interventional cardiologist, Primus Super Speciality Hospital, said.
He said that over time, it may contribute to the development of atherosclerosis (hardening and narrowing of arteries) and increase the risk of heart disease.
Agreeing, Dr Rinky Kapoor, consultant dermatologist, cosmetic dermatologist and dermato-surgeon, The Esthetic Clinics explained that people with psoriasis often have elevated levels of cytokines and immune system proteins that promote inflammation in the city.
“These cytokines can contribute to the formation of plaques in arteries, leading to atherosclerosis. Moreover, psoriasis increases the likelihood of metabolic syndrome—conditions including high blood pressure, increased blood sugar levels, excess body fat around the waistline, and abnormal cholesterol levels. This syndrome is known to increase the risk of heart disease and stroke,” she added.
People with psoriasis should keep their heart health in check (Source: Getty Images)
According to Dr Kapoor, psoriasis sufferers may also be more prone to activities that negatively impact cardiovascular health, such as smoking or a sedentary lifestyle due to reduced physical activity, stemming from feelings of self-consciousness or discomfort associated with visible skin lesions.
Severe psoriasis, especially, can have a more significant impact on heart health due to its prolonged and widespread inflammation. This inflammation can lead to the buildup of plaque in arteries, potentially causing heart attacks, strokes, or other cardiovascular problems.
“Additionally, individuals with severe psoriasis may be more likely to have risk factors like obesity and metabolic syndrome, which further elevate their heart disease risk,” Dr Chopra said.
While there is currently no known cure for psoriasis, experts mentioned that there are several steps you can take to prevent flare-ups and manage the symptoms effectively.
*It’s important to maintain a healthy diet and lifestyle. Make sure to include plenty of fruits, vegetables, whole grains, and lean proteins in your daily meals. Avoid processed foods, sugary snacks, alcohol, and smoking as they can trigger inflammation in the body.
*Managing stress levels is crucial for preventing psoriasis outbreaks. High stress levels have been found to worsen existing symptoms or trigger new episodes. Consider incorporating relaxation techniques such as yoga, meditation, or deep breathing exercises into your routine to help reduce stress.
*Taking care of your skin is essential in preventing psoriasis flare-ups. Keep your skin moisturised with gentle moisturisers that lock in moisture after bathing or showering. Avoid harsh soaps or cleansers that can strip away natural oils from the skin.
As for managing your heart health, Dr Chopra emphasised the need to undergo regular medical check-ups, including monitoring blood pressure, cholesterol levels, and glucose levels, which are crucial.
“Lifestyle changes like a heart-healthy diet, regular exercise, and stress reduction techniques can be beneficial. Moreover, working closely with healthcare providers to tailor treatment plans is essential to minimise inflammation and reduce cardiovascular risks. Psoriasis patients may need more proactive heart disease prevention strategies due to their increased risk,” he concluded.
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