Updated: November 18, 2021 8:48:20 am
Global antibiotic consumption rates increased by 46% in the last two decades, according to a study covering 204 countries from 2000 to 2018, and published in the Lancet Planetary Health by the Global Research on Antimicrobial Resistance (GRAM) Project.
GRAM used a novel approach that deployed statistical modelling techniques, and incorporated multiple data sources and types, such as large-scale household surveys in low-and middle-income countries, pharmaceutical sales data, and antibiotic consumption data from the World Health Organization (WHO) and the European Centre for Disease Prevention and Control (ECDC), the University of Oxford said in a press release (GRAM includes researchers from Oxford).
The study provides a comparative analysis of total antibiotic consumption rates in humans globally, expressed in the WHO metric of defined daily doses (DDD) per 1,000 population per day.
The key findings:
10-fold: Variation between countries in total antibiotic consumption rates, ranging from as low as 5 DDD to 45.9 DDD per 1000 population per day.
46% up: Between 2000 and 2018, global antibiotic consumption rates increased from 9.8 to 14.3 DDD per 1000 population per day).
76%: Increase observed between 2000 and 2018 in low- and middle-income countries (from 7.4 to 13.1 DDD per 1000 per day). In high-income countries, consumption rates remained stable.
116%: Increase in antibiotic consumption rates in South Asia. The second largest increase was in the North Africa and Middle East region (111%).
Excess and inappropriate use of antibiotics is an important driver of drug resistant infections, the release said. It quoted Professor Christiane Dolecek, the study’s lead author, as saying: “These findings reveal the huge task ahead, implementing and delivering the WHO Global Action Plan on Antimicrobial Resistance, which relies on optimising antibiotic use and reducing the incidence of infections.”
Source: University of Oxford
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