scorecardresearch
Tuesday, Nov 29, 2022

New research: An oral version of remdesivir

Manufacturer Gilead Sciences has partnered with researchers in Georgia State University to test a modified version of remdesivir that can be taken orally.

An ampule of Gilead Sciences Covid-19 antiviral remdesivir. (Ulrich Perrey/Pool via Reuters/File Photo)

Remdesivir, which was once considered the most promising of the Covid-19 treatments that went through the Solidarity trials under the aegis of the World Health Organization (WHO), but which has since fallen out of favour, is delivered intravenously.

Now, manufacturer Gilead Sciences has partnered with researchers in Georgia State University to test a modified version of remdesivir that can be taken orally.

The research comes at a time when Merck and Ridgeback’s oral drug for Covid-19, molnupiravir, has received clearance from the UK, and when Pfizer has reported promising trial results of its own Covid-19 drug, Paxlovid. (Read more about it here)

On November 20, the WHO issued a conditional recommendation against the use of remdesivir in hospitalised patients, regardless of disease severity, as “there is currently no evidence that remdesivir improves survival and other outcomes in these patients”.

Subscriber Only Stories
Delhi Confidential: Ahead of Gujarat polls, BJP worries about NOTA votesPremium
Agrarian Punjab diesel-driven; Delhi opts for cleaner optionsPremium
The shadow of 1979: Iran and Saudi Arabia are fighting Islamism; Pakistan...Premium
Geniben Thakor interview: ‘BJP’s choice of a Thakor candidate...Premium

Researchers have now reported that the modified version of remdesivir was “highly effective” in suppressing SARS-CoV-2 replication and transmission in animals when given orally.

It could be “groundbreaking” in improving patient access to treatment early after infection, Georgia State University said in a press release.

The results of the study, done on ferrets, have been published in the journal Nature Communications.

First published on: 09-11-2021 at 10:28:00 am
Next Story

CBSE Class 10th 12th Term-1 Exams 2022 released: How to download admit card

Latest Comment
Post Comment
Read Comments
Advertisement
Advertisement
Advertisement
Advertisement
close