Jai Singh Rathore and ATU have finally caught Suraj, the virus dealer. Assuming that the two Serchan brothers are dead and six virus tubes are under ATU’s control, Shivani Malik informs PM about the success of the mission.
Roshan, who had escaped into the jungle, calls up his aide asking them to arrange for a boat jetty to Mumbai and informs them of Haroon’s death. Roshan Serchan is now determined than ever to destroy Mumbai and the country using the bio lethal virus.
However, PM Aditya Singhani calls for scientists to develop an antidote for the virus. Presuming that the virus and the terrorists are under control, the PMO is dismissed and Prithvi’s affair takes the center place with PM and Naina Singhania.
Maya, though escapes from Haroons place with her father, but is caught by ATU while her father is being killed in a tiff with Serchan’s goon.
ATU team, however, unlocks the virus briefcase to find out only five tubes, while one is still missing. But, in no time Jai, the smart patriot, on the basis of Roshan’s medical history informs that Roshan has escaped with that one virus capsule and would probably be heading to Mumbai. Following this, Mumbai is put on high alert and search for Roshan is on.
Jai, meanwhile, returns to ATU where he is informed about Home Ministry setting up an inquiry against him. Here comes the grand entry of veteran actress Shabana Azimi – playing Abhilasha Grewal, former ATU chief. She along with Ronit Roy is to enquire Jai Singh Rathore. They are to question him about the unauthorized under cover mission. Not to forget that Abhilasha has a record of animosity and bitterness with Jai Singh Rathore since the first season.
On the other hand Naina Singhania is busy unearthing Shantaram, the game changer for Amar Mane Shinde’s survival in politics. The story weaves up in the backdrop of March 2006, when Shantaram was paid a hefty amount to keep mum as a witness in the killing of his daughter by a car driven by Amar Mane Shinde. Also, Shantaram’s son Yashwant is a convicted criminal and is serving a jail term. Naina, on the promise of setting his son free, asks Shantaram to unveil Mane Shinde in media. Shantaram agrees to her offer.