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Hyderabad: 54% population developed antibodies against Covid-19, says latest sero survey

The survey also revealed that more than 75 per cent of the seropositive population did not know they had contracted coronavirus infection in the past.

According to the study, individuals who had prominent Covid-19 symptoms as well as those who were asymptomatic were found to have equivalent seroprevalence of around 54 per cent.

The latest seroprevelance survey in Hyderabad has revealed that around 54 per cent of the city’s residents have developed antibodies against SARS-CoV-2, indicating prior exposure to the coronavirus. The survey also revealed that more than 75 per cent of the seropositive population did not know they had contracted coronavirus infection in the past.

The study, which was jointly conducted by CSIR – Centre for Cellular and Molecular Biology (CCMB), ICMR – National Institute of Nutrition (NIN) and Bharat Biotech, was aimed at estimating the seroprevalence of antibodies against the coronavirus in Hyderabad.

The scientists checked over 9,000 samples for antibodies against the virus in people from across 30 wards of the city. At least 300 people from each ward, all of them older than 10 years of age, were tested during the survey.

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Most of the wards showed a similarly uniform range of seroprevalence from 50-60 per cent. However, a few wards showed as much as 70 per cent or as low as 30 per cent seroprevalence as well.

Women showed a marginally higher seropositivity rate (56 per cent) than men (53 per cent). Those above 70 years of age showed a lower seropositivity (49 per cent), possibly because of limited mobility and extra care taken by older individuals during the pandemic.

Not surprisingly, those who had Covid-19 positive cases in their own households, showed the maximum seropositivity of 78 per cent, according to the study. This was followed by those with known Covid-19 contacts outside their household (68 per cent).

In a press statement, Dr A Laxmaiah, Scientist ‘G’ at the NIN, observed that having a larger number of rooms in houses and small family size households had low prevalence of coronavirus infection.

“This multistage random sampling study on 9000 people in the city of Hyderabad showed that more than 75 per cent of the seropositive population did not know that they had contracted coronavirus infection in the past. This suggests seroconversion, that is antibody formation has happened even with silent infections, “said Dr R Hemalatha, Director, NIN.

According to the study, individuals who had prominent Covid-19 symptoms, as well as those who were asymptomatic, were found to have equivalent seroprevalence of around 54 per cent.

About 18 per cent of the study group had been tested earlier and were found positive for the coronavirus. At least 90 per cent of them were found to be seropositive, suggesting that they retain the antibody response.

“This study brings a comprehensive perspective of the potentially protective immune response against the coronavirus in the city’s population. The data indicates that the population of Hyderabad might be slowly moving. towards herd immunity, which will be certainly accelerated by the ongoing Vaccination effort, “said Dr Rakesh Mishra, Director, CCMB.

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