The mortality rate in patients having Acute Coronary Syndrome with Cardiogenic Shock has been recorded as 35 per cent which is the least as compared to mortality rates in other centres across the globe, a study by the Advanced Cardiac Centre of PGIMER has found.
Cardiogenic shock (CS) is a severe situation after heart attack in which the heart fails to pump blood to the body and is the leading cause of death in heart patients.
This study conducted by the head of department, Prof Yash Paul Sharma, along with a team of doctors of the cardiac centre has been accepted by the Indian Heart Journal for publication and will now be presented at Cardiology Society of India (CSI) in the last week of November. With this, PGI now claims to have the least mortality rate in these patients in the world. According to the institute, the present mortality rates in literature published from different centres across the world is about 60 per cent in cardiogenic shock cases. While medical intervention is not timely, the mortality rate is high from 70 to 90 per cent as well.
From June 2017 to May 2018, a total of 150 cardiogenic shock patients reporting at the PGI were studied. Mean age of the patients taken for the study was 58 years which, according to the PGI, was almost a decade younger than the western counterparts. These patients had multiple comorbidities or multiple chronic situations like diabetes, anaemia, renal dysfunction and sepsis.
More than 50 per cent of these 150 patients who were studied had undergone coronary angiography that showed a single artery disease in most of them. About 40 per cent patients had risk factors only like smoking, diabetes and hypertension.
Prof Sharma stated that the role of treating anaemia, strict monitoring and judicious correction of intravascular volume (volume of blood), albumin and treating these patients with precision in cardiac treatment has contributed to the decrease in the mortality.
“All this shows chances of survival rates for severe coronary artery disease are increasing which is a good sign. We have also been emphasizing the role of treating anaemia in heart patients as it is a major factor in decreasing the mortality. This result obtained is a record in the history of medical literature that mortality has been found the least, up to 35 per cent,” Prof Sharma said.
He added, “In 100 patients of Acute Coronary Syndrome, around eight patients have cardiogenic shock disease. Out of these eight patients, through conventional treatment, five to six patients had mortality. But with new innovative, integrated patient-specific approach and with continuous monitoring, multi-modality treatment, mortality has reduced to two to three patients. All these augur a better future for coronary artery disease.”
The study also revealed that the average median time (time when a person suffers chest pain and the time when he reaches hospital for treatment) in these patients was 12 hours which indicated that there is a significant delay in seeking medical attention. The doctors said that in case a patient suffers chest pain, he must report to the hospital as soon as possible.