Harris, 54, the daughter of immigrants from Jamaica and India, enters the race with the potential advantage of being the Democratic candidate who looks most like the party's increasingly diverse base of young, female and minority voters.
Raj Shah's departure comes as the White House press and communications teams have been depleted. Several aides have moved on to roles at government agencies or have left the Trump administration entirely.
In a sign of growing unease about the partial government shutdown, some Senate Republicans came off the sidelines to hash out a deal that would reopen the government as Congress worked toward a broader agreement tying wall funds to protection for some immigrants in the country illegally and other migrants.
The White House has directed the Army Corps of Engineers to examine emergency supplemental funds allocated last year after devastating hurricanes and wildfires that could instead be used to pay for the wall.
Trump's posts were replete with grievances about funds for border security, the Federal Reserve chairman, Democrats critical of his relationship with U.S. allies and Brett McGurk, the departing special envoy for the coalition fighting the Islamic State group.
According to the document, the United States is aiming to secure duty-free market access for American industrial products and reduce or eliminate tariffs for US agricultural goods. It may want to negotiate the deal in stages.
"The president, and especially the White House press secretary, should understand their words matter," said Jeff Zucker, president of CNN Worldwide. "Thus far, they have shown no comprehension of that."
Ever wondered how the first family of the US celebrates Christmas? You may not be invited for the eggnog, but you can at least take a sneak peak at the decorations that adorn the White House this holiday season.