Neymar limped off with a recurrence of a right-foot injury during Paris Saint-Germain's 2-0 French Cup win against Strasbourg on Wednesday, casting doubt whether he will face Manchester United in the first leg of their Champions League last-16 match
PSG set out like a team determined finally to prove their credentials on the big European stage, and went in front in the 13th minute through Juan Bernat, before Neymar made it 2-0 eight minutes before halftime.
Mbappe and Neymar sat out Saturday's 1-0 win over Toulouse in the French league and were doubtful for the match against Liverpool after they picked injuries with their national teams during friendly games.
Neymar was again the stand-out Brazil player and he coolly side-footed home his 60th international goal in the 76th minute after Diego Laxalt brought down Danilo, although Uruguay claimed there was a handball in the build-up.
Barcelona's Neymar is all set to leave the club after serving his best four years. He scored 105 goals in 186 appearances for Barcelona. His best season for the club came in 2014-15, where he managed to score 39 goals. He is likely to join Paris Saint Germain for a record fee.