Attahullah Khogyani, spokesman for the governor in eastern Nangarhar province, says that along with the 16 killed, nine other people were wounded when the militants launched a suicide bombing and stormed a construction company near the airport.
A senior security official said the blast happened close to a compound of British security contractor group G4S, near an industrial park on the main road leading out of Kabul towards eastern Afghanistan.
Afghanistan blast: Most of those killed, including the politician Avtar Singh Khalsa, were travelling to meet President Ashraf Ghani. Khalsa, 52, is survived by his wife and four children. One of his sons, Narinder Singh Khalsa, was injured in the attack.
Ghulam Sanayi Stanekzai, police chief of Nangarhar said the explosion was caused by a suicide bomber who targeted a vehicle carrying members of the Sikh minority who were travelling to meet the president. Officials said at least 10 of the dead were Sikhs.