The Indian challenge at the second Grand Slam of the season will be led by world number one Sania Mirza in women’s doubles.
Nadal is approaching his 29th birthday and major questions about his form and confidence.
Nadal beaten 7-6 (7), 6-2 by Wawrinka in the Italian Open quarterfinals on Friday, his fifth loss on clay this season.
Maria Sharapova claimed her fifth Grand Slam, defeating Simona Halep in marathon encounter.
Halep bowed out after three hours and two minutes – the longest women’s final in Paris since 1996.
Sharapova overwhelmed Romania’s Halep 1-6 6-2 6-3 in the Madrid Open final last month.
This is Sharapova’s 3rd consecutive French Open final after she defeated Bouchard 4-6, 7-5, 6-2 in the semis.
Latvian Ernests Gulbis hands the Swiss champion his earliest exit at the French Open in a decade.
Federer has bowed out before quarters at three of last four majors, including fourth-round loss at U.S. Open.
Nadal’s injury from Aus Open acts up again even as World No.1 matches French Open streak.
For second time in his French Open career, Nadal owns a 31-match winning streak at the clay-court Grand Slam.
Polish follows Serena and Li Na home, the first time since 1968 that top three seeds fail to reach Round Four.
Djokovic won 6-3, 6-2, 6-7 (2), 6-4 against Cilic. Meanwhile, Federer defeated Tursunov 7-5, 6-7 (7), 6-2, 6-4.
Nadal’s French Open record stands at 61-1 currently and his dominance shows no sign of fading.
Eight-time champion and holder dominates Australian Thiem in straight sets to move into third round.