A win on the famed Brickyard oval would be sensational but the double world champion will still have to conquer the Le Mans 24 Hours sportscar race.
British Formula Four driver Billy Monger has had his lower legs amputated after smashing at speed into the back of another car.
One of the instructions came in the closing stages, when Bottas was ordered to let Hamilton pass so he could chase down Ferrari's Sebastian Vettel.
The Spaniard left the pitlane and collided with Lance Stroll's Williams just as the 18-year-old Canadian rookie was turning into the first corner on lap 13.
Lewis Hamilton had missed out on a seventh successive pole on Saturday, with Bottas beating him to it.
Sebastian Vettel, now seven points clear of Lewis Hamilton is enjoying his best start to a season since his dominant 2011 Red Bull campaign.
Twice Valtteri Bottas let Lewis Hamilton through to try and take on Vettel, but it went in vain as the Briton ended up second and Bottas third.
Lewis Hamilton finished almost seven seconds behind Sebastian Vettel despite was catching the German on every lap.
Alonso's engine failed early into qualifying on Saturday for the Bahrain Grand Prix, pushing him to 15th place on the grid.
Lewis Hamilton qualified alongside, a mere 0.023 - or 17 centimetres - slower than Valtteri Bottas's time of one minute 28.769 seconds.
Lewis Hamilton qualified 0.023 seconds slower than Vallteri Bottas to qualify second and form a Mercedes front grid at the Bahrain Grand Prix.
Max Verstappen managed to push Ferrari and Mercedes off the top of the timesheets in the final practice at Bahrain.
Champions Mercedes and rivals Ferrari have become the pacesetters, with Sebastian Vettel leading the standings jointly with Lewis Hamilton.
The four times world champion lapped 0.400 faster than Red Bull's Australian Daniel Ricciardo in the afternoon.
Bernie Ecclestone was appointed 'chairman emeritus', a job with no defined role, after being moved away from the helm.
Liberty CEO Greg Maffei had said that the Azerbaijan GP did "nothing to build the long-term brand and health of the business".
Sebastian Vettel beat Mercedes driver Valtteri Bottas by just .041 in the second session under floodlights.
Jenson Button will stand in for Fernando Alonso at Monaco GP while the Spaniard competes in the Indianapolis 500.
McLaren have yet to say who will be the stand-in, but Jenson Button is looking like the clear frontrunner.
Fernando Alonso will miss the showcase Monaco Grand Prix to race in the 101st edition of the U.S. race
The revamped Formula One season has thus far lived up to the hype as Lewis Hamilton and Sebastian Vettel have won a race apiece.
Monaco is the most glamorous race track and it is unheard of in modern times for a top driver to miss it of his own volition or for a team to let him.
The British-based team hasn't announced who will replace Fernando Alonso for the most glitzy race on the F1 calendar.
Ruhaan Alva won the Easykart Championship in Lonato in Italy, overtaking two front runners on the last lap.
Lewis Hamilton and Sebastian Vettel are locked on 43 points apiece on top of the standings heading into the next round in Bahrain Grand Prix.
Max Verstappen finished third in the Chinese GP despite being second to last in qualifying.
Sergio Perez and Esteban Ocon finished ninth and tenth respectively in the Chinese GP.
Red Bull and Force India drivers failed to join the rest in standing at the front of the grid 14 minutes before the start of the formation lap.
Lewis Hamilton started from pole position and led from beginning to end to capture the 54th race title of his career.
FIA has designated two hospitals to provide medical care for Sunday's race, the Huashan Hospital and the Ruijin Hospital.
Max Verstappen was 19th-fastest of 20 cars in qualifying in Shanghai, after nursing engine problems. But he will start at least two places higher.
Fernando Alonso eventually ended up 13th on the timesheets, failing to make it through to the final pole-position shootout phase.
Sergio Perez clocked the eighth fastest time for Force India while teammate Esteban Ocon was eliminated in Q1.
Niki Lauda being too happy about losing money, but there is one wager he must have been delighted to lose at the Chinese GP.
Lewis Hamilton's time of 1 minute, 31.678 seconds broke the 13-year-old mark held by Michael Schumacher at the Shanghai International Circuit.
The bitter rivalry between the former childhood friends meant Mercedes' management often had to walk a fine line.