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New drug may treat both diabetes and bone loss

The new dual-targeting drug candidate, referenced as "SR10171.", could treat both diabetes and bone disease.

By: IANS | New York | Published: July 28, 2016 2:28 pm
Dilshad Garden, blood sugar, diabetic families, joint families, nuclear families, Type 2 diabetes mellitus, diabetes, T2DM, health news, India news, national news, latest news, Delhi news Improve body mass index and treat diabetes. (File)

Researchers have developed a new class of compound that has shown promise in treating both diabetes and bone disease.

In addition to its more obvious ills, Type-2 diabetes is a condition closely associated with bone fractures, increasing the risk of fractures twofold. To make matters worse, certain anti-diabetic drugs further increase this risk, particularly in postmenopausal women, severely limiting their treatment options.

But the new dual-targeting drug candidate, referenced as “SR10171.”, could treat both diabetes and bone disease. “SR10171 improves bone mass regardless of body mass index, normal to obese,” said co-lead researcher Patrick Griffin, professor at the Florida campus of The Scripps Research Institute (TSRI) in the US.

“So you could use such a drug to treat osteoporosis whether patients are diabetic or not,” Griffin added. The drug increases bone mass by expanding bone formation (deposition of new bone) and bone turnover (a normal process of replacement of old bone).

A proper balance of these two processes is critical to healthy bone maintenance, and this balance is frequently negatively affected in diabetic patients. In animal models treated with the compound, fat formation in the bone marrow was successfully blocked independent of their metabolic state (healthy or diabetic), showed the study published online in the journal EbioMedicine.

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  1. D
    Jul 29, 2016 at 11:59 am
    If he blows this one thing, you are toast...And nearly every doctor, dieian, and healthexpert gets it wrong!lt;br/gt;How do I know? Because what I’ve uncovered and tested with my own clients and my own father is nothing short of amazing.lt;br/gt;And I’m shocked that it’s still not yet common knowledge, especially for diabetics who need itthe most.lt;br/gt;My name is Yuri Elkaim. I’m a New York Times bestselling author, renowned nutritionist, andI’ve helped more than 500,000 to amazing health over the past 15 years.lt;br/gt;Even then, I’m unaware of any diabetic client that has come to me and said that their doctor or dieian has recommended they eat more of the mysterious super starch..lt;br/gt;Eating this“super starch” may not sound like a big deal at first, but when it comes to diabetes, it's huge...lt;br/gt;As you’re about to discover, this could be the simplest and most powerful tactic you employ to…
    1. S
      Jul 28, 2016 at 9:52 am
      A very welcome development indeed!
      1. S
        Sankaran Krishnan
        Jul 29, 2016 at 2:05 pm
        This new drug will be welcomed by those who are all suffering with both the diseases and it is a boon for the women patients who suffers mostly with bone loss. Please do ensure the price is moderate and affordable to the middle cl !!!
        1. Allen Samantha
          Jul 28, 2016 at 10:20 am
          We can reverse diabetes through exercise and healthy eating.Losing 5% to 10% of your body weight and building up to 150 minutes of exercise a week may help you to slow or stop the progress of type 2 diabetes. I actually read an article about diabetes curing diet and it seemed like the person had great success so I gave it a try. I couldn’t have been more excited about the results, as I am now 50 pounds lighter than when I first started using it. The article was very helpful to me -- if you want to check it out yourself you can read it here (google " CURE DIABETES PRO.GQ " )