High Vitamin D levels in childhood may cut diabetes risk

Vitamin D represents a candidate protective factor for Type 1 diabetes as it regulates the immune system and autoimmunity, the researchers said.

By: IANS | New York | Published:October 24, 2017 11:59 am
diabetes risk, diabetes in kids, Vitamin d deficiency, Type 1 diabetes, immune system, islet cells, immune system, author Jill Norris, indian express, indian express news More Vitamin D can lower risk of developing diabetes. (Source: File Photo)

Children who receive higher levels of Vitamin D during infancy and childhood may be significantly at a lower risk of developing islet autoimmunity as well as Type 1 diabetes, according to a study. Type 1 diabetes is a chronic autoimmune disease that is increasing by 3-5 per cent annually worldwide and occurs when the body’s immune system destroys its own insulin-producing beta cells in the pancreas.

Islet autoimmunity, detected by antibodies that appear when the immune system attacks the islet cells in the pancreas that produce insulin, is a precursor to Type 1 diabetes. “For several years there has been controversy among scientists about whether Vitamin D lowers the risk of developing of islet autoimmunity and Type 1 diabetes,” said lead author Jill Norris from the Colorado University – Anschutz.

In the study, published in the journal Diabetes, the team searched for triggers and protective factors in 8,676 children with elevated Type 1 diabetes risk. They identified islet autoimmunity in 376 children and compared them with 1,041 children who did not.

Among children who were at an increased genetic risk for Type 1 diabetes, those with lower Vitamin D levels in infancy and childhood went on to develop islet autoimmunity compared with those who did not develop autoimmunity.

The study showed that higher childhood vitamin D levels are significantly associated with a decreased risk of islet autoimmunity.

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