If you are strict with your diet during the week and eat junk over the weekend, then may be you are undoing all the good work done during the week.
The human gut consists of up to 100 trillion microbial cells that influence metabolism, nutrition and immune function. Disruption to the gut microbiota has been linked with gastrointestinal conditions — such as inflammatory bowel disease and obesity.
“The study was the first to compare how continuous — or intermittent — exposure to an unhealthy diet can impact the composition of the gut microbiota,” said lead author Margaret Morris from the University of New South Wales in Australia in the journal Molecular Nutrition and Food Research.
“A reduction in the diversity of the gut’s microbiota, and a loss of some of the beneficial biota is clearly not a good thing for health,” Morris stated.
The study examined the impact of yo-yo dieting on the gut microbiota of rats. “The findings indicate that intermittent exposure to junk food three days a week is sufficient to extensively shift the gut microbiota towards the pattern seen in obese rats consuming the diet continuously,” Morris added.
The research team compared the abundance of microbiota in rats given continuous access to either a healthy diet or junk food with a group cycled between the two diets — healthy for four days and junk for three — over 16 weeks.
The study showed that rats on the cycled diet were 18 per cent heavier than those on the healthy diet, while leptin and insulin levels in cycled rats were in between levels of rats fed junk or healthy food. The microbiota of cycled rats was almost indistinguishable from rats fed a constant diet of junk — with both groups’ microbiota significantly different from those in the rats fed a healthy diet — the researchers found.