Chikungunya spurt could be due to ‘evolution’ of viral strain, say Experts

People in North India are more vulnerable to the disease because unlike people in South they haven't been really exposed to the chikungunya strain, said Municipal Health Officer of SDMC, P K Hazarik

By: PTI | New Delhi | Published:September 15, 2016 4:12 pm
Chikungunya, Chikungunya in NCR, Chikungunya Virus, Chikungunya Spread in Delhi-NCR, Chikungunya death toll, Chikungunya affected patients in Delhi NCR, Chikungunya Symptoms, Chikungunya news, National Vector Borne Disease Control Programme, Chikungunya diagnosis, Latest Medical news, medical news, The number of chikungunya cases in the national capital have climbed to over 1,700 this season and at least 12 deaths have been reported due to the disease. (Representational Picture)

As the number of deaths in Delhi due to chikungunya and its complications have shown a spike, health experts say the sudden “upsurge” of the disease this year could be a result of “evolution” of the viral strain.

Doctors have detected that the viral strain is showing “different behaviour”, though it will only be conclusive once research is conducted on the make up of the virus.

“Dengue and chikungunya both are caused by the same aedes mosquito but dengue can be contracted through four viral strains while chikungunya is caused only by one strain. Also, in dengue cases, some strains are more virulent than other ones. The number of rising cases of chikungunya this year after the 2006 spike could be due to an evolution in its strain,” National Vector Borne Disease Control Programme (NVBDCP) Director A C Dhariwal said.

Experts also feel that north Indians could be succumbing to the vector-borne disease because of their “low immunity” to it.

“People in north India haven’t been really exposed to the chikungunya strain compared to the population in the southern part of the country, and therefore they are more vulnerable to this viral attack,” Municipal Health Officer of SDMC, P K Hazarika told PTI.

He, however, said the probability of evolution of the viral strain will just be a speculation until scientists establish it.

IgM-ELISA and Reverse Transcription-Polymerase Chain Reaction (RT-PCR) are the two main tests used to detect chikungunya in patients.

A senior doctor at Sir Ganga Ram Hospital says the viral strain in patients diagnosed with chikungunya at its hospital are “showing different behaviour” for the two tests.

“We used IgM serology on patients earlier but then after finding discrepancy between clinical diagnosis and laboratory tests, we started performing molecular test (RT-PCR) to detect the chikungunya virus from the blood of clinically suspected patients from September 1 onwards,” the doctor said.

“And from Sep 1-13, out of 565 samples of suspected viral fever, 319 came positive for chikungunya virus which is about 56 per cent positivity. So, we found out that a test coming negative by IgM is coming positive by RT-PCR. And, this could mean the number of cases in Delhi could be much higher than currently reported,” he said.

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Arun R Kaushik, specialist in microbiology and geriatrics, says, “Chikungunya virus is transmitted by the bite of aedes albopictus and aedes aegypti mosquitoes. The risk of death is about one in 1,000 especially common among the elderly or those with underlying chronic medical problems.”

According to the Bangalore-based doctor, “The prevalence of arbovirus infections similar to chikungunya virus in south India especially in states like Karnataka, Tamil Nadu have made people tolerant to these infections.”

The number of chikungunya cases in the national capital have climbed to over 1,700 this season and at least 12 deaths have been reported due to the disease.